Bone mineral density of the lumbar spine after percutaneous vertebroplasty in patients with osteoporosis

V.O. Radchenko, V.K. Piontkovsky, A.I. Popov, N.V. Dedukh, S.B. Kosterin, V.E. Maltsevа


Background. Today, the most common procedures in case of osteoporotic vertebral body fractures are percutaneous vertebroplasty and percutaneous balloon kyphoplasty. Bone cement, which is used for these procedures, stabilizes the vertebral body after osteoporotic fracture and contributes to increasing of strength. The purpose of the study was to determine the bone mineral density (BMD) in the vertebral bodies adjacent to the vertebral body with vertebroplasty and adjacent, according to examination of patients with osteoporosis on a bone densitometer. Materials and methods. An Explorer QDR bone densitometer (Hologic) was used to study the lumbar spine BMD in 20 postmenopausal women 6 months, a year and two years after percutaneous vertebroplasty. Bone cement was injected into the vertebral bodies with low BMD in case of compression fracture for its consolidation or symptomatic osteoporosis established in terms of X-ray, densitometry, computed tomography or magnetic resonance imaging. Results. Analysis of BMD in female patients with osteoporosis after percutaneous vertebroplasty performed on 1–3 vertebrae of the lumbar spine showed that if there are compression fractures and anti-osteoporosis therapy, the indicators of BMD do not decrease. However, all patients in the vertebrae without vertebroplasty have osteoporotic manifestations for different periods of the study (from 6 months to 2 years). Fundamental diffe-rences in BMD indices at the level of the vertebrae located above or below the vertebra with bone cement, as well as between vertebrae with vertebroplasty, have not been established. The obtained data should be considered when it is necessary to install fixing structures in the vertebral body. Conclusions. Regardless of the level of performance of vertebroplasty in patients with osteoporosis, when prescribing anti-osteoporosis therapy, there are no significant changes in BMD indices in the vertebrae adjacent to the operated one and adjacent to it. Patients after vertebroplasty should be prescribed anti-osteoporosis therapy for a long period.


bone mineral density; vertebroplasty; adjacent vertebrae


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