Prospects for the quantitative assessment of the results of single-photon emission computed tomography of the skeletal system (literature review)

P.O. Korol, A.V. Samokhin, M.M. Tkachenko


The review of the literature examines the prospects for the quantitative assessment of the results of single-photon emission computed tomography (SPECT) of the skeletal system. Synthesis of functional information obtained using SPECT together with high resolution computed tomography allows you to effectively determine the pathological metabolism in the bones with the simultaneous assessment of coexisting structural changes. Indicators of the maximum standardized uptake value of the radiopharmaceutical and the peak standardized uptake value should be considered the most optimal parameters for the quantitative determination of the focal absorption of radiopharmaceutical. In the future, it is necessary to attract narrower subgroups of patients (for example, by age, height, weight, sex, etc.) that have specific conditions in order to create an appropriate evidence base. However, further technological improvements are needed to make the calculation of quantitative SPECT parameters, by determining the standardized uptake value, a part of normal medical practice.


single-photon emission computed tomography; radiopharmaceutical; standardized uptake value; review


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