Current experience of using SPECT/CT in patients with bone pathology (literature review)


  • P.A. Korol Bogomolets National Medical University, Kyiv, Ukraine; Kyiv City Clinical Hospital 12, Kyiv, Ukraine,
  • M.N. Tkachenko Bogomolets National Medical University, Kyiv, Ukraine,



single-photon emission computed tomography, hybrid imaging, nuclear medicine, radiopharmaceutical, review


The review discusses the results of a twenty-year experience using single-photon emission computed tomography/computed tomography (SPECT/CT). Hybrid imaging, including the use of SPECT in combination with CT, translates molecular and metabolic information directly onto the clinical effect of a wide range of diseases of the skeletal system. At the same time, SPECT/CT further improve the diagnostic accuracy, specificity, and positive prognostic value of nuclear medicine research. It was considered expedient to carry out a review of modern SPECT/CT application not only from the perspective of a diagnostic tool but to integrate this modality into the clinical process. To this end, complex technical issues are being resolved for attracting new radiopharmaceuticals to use SPECT/CT, improving the quality of protocols for obtaining diagnostic images, quantifying them, as well as compiling protocols for dosimetry and radiation exposure that are beyond the scope of the current review.


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