Results of Osteosynthesis of Pathological Fractures of Long Bones with Metastatic Tumors

V.V. Protsenko, O.V. Ilnitskyi, V.S. Chornyi

Abstract


The article reported the results of osteosynthesis in 65 patients with pathological fractures on the background of metastatic bone lesions. We have applied such methods of osteosynthesis: perosseous osteosynthesis with external fixation device — in 33 (50.8 %) patients, reinforced osteosynthesis — in 32 (49.2 %). Osteosynthesis has been applied in comprehensive treatment using polychemotherapy, radiation therapy, hormone therapy, immunotherapy and bisphosphonates. Due to the use of osteosynthesis techniques in complex treatment regimens, complications occurred in 2 (3.1 %) patients, recurrences of metastatic tumors — in 3 (4.6 %) patients, new foci of metastatic lesions in bones and visceral organs during the treatment were detected in 35 ( 53.8 %) patients. The three-year overall survival rate of patients was 28.60 ± 1.32 %, five-year — 14.40 ± 1.96 %. The use of osteosynthesis techniques in the comprehensive treatment in patients with metastatic lesions of long bones helps to restore the function and support ability of the limb, to reduce pain and therefore to improve the quality of life of these patients.


Keywords


metastasis to bones; fixation; reinforced osteosynthesis; perosseous osteosynthesis with external fixation device

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DOI: https://doi.org/10.22141/1608-1706.2.17.2016.74654

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