The Strength of Bone-Metal Block for Different Types of Implants Surfaces under the Conditions of Normal Bone and Osteoporosis in Experimental Rats

V.A. Filippenko, S.Ye. Bondarenko, M.Yu. Karpinsky, A.I. Zhygun, V.A. Tankut, M. Akonjom


Fixing the acetabular component of prosthesis in the conditions of osteoporosis and changes in acetabulum anatomy is a topic problem in modern orthopedics. Aim: to perform a comparative analysis of the strength of bone-metal block for the different type of implant surfaces under the conditions of normal bone and in the simulative osteoporosis in rats. Methods. The experimental studies of femur strength were carried in 60 laboratory animals (rats). The animals were divided into two groups of 30 animals each: I — relatively healthy, II — osteoporosis induced by ovariectomy. Six subgroups were formed in each group of animals. Implants of such different materials as porous titanium, tantalum porous Trabecular Metal (Zimmer), titanium coated with Gription (DePuy), Stiktite (Smith & Nephew), Trabecular Titanium (Lima), Tritanum (Stryker) were used to fill a hole-like defect in distal metaphysis of femur. The animals were taken out of experiment 90 days after implantation and biomechanical investigation was performed to assess the strength of operated and contralateral femurs. Longitudinal axial load using a metal rod was applied to femoral head. Load value gradually increased to complete destruction of anatomical specimen and measured. Results. Femurs with implants from porous tantalum Trabecular Metal and Stiktite withstood the maximum load in the conditions of normal bone density. Specimen of femurs with implanted porous titanium (the most weak) and tantalum Trabecular Metal (the most solid) composed separate subsets under the conditions of simulated osteoporosis. Conclusions. The comparative analysis of biomechanical investigation revealed that bone with implants from porous tantalum withstands the maximum breaking load under the conditions of normal and osteoporotic bone.


implants surface; bone-metal block; osteointegration; arthroplasy


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