The Risk of Nosocomial Infection Development in Patients with Severe Combined Abdominal Trauma

G.G. Roschin, V.I. Ivanov, V.M. Dorosh

Abstract


According to the results of multifactorial prospective study of the treatment of 41 patients with severe combined abdominal trauma using the principal of individual empiric de-escalation antibiotic treatment there were assessed the morbidity of the pathology associated with ESKAPE agents for hospital-acquired infections. The morbidity of the pathology associated with hospital-acquired infection is connected firstly with Pseudomonas aeruginoza (58.5 %) and Klebsielia pneumoniae (56.1 %) with odds ratio for hospital-acquired infection development 1.41 и 1.28, respectively.
According to clinical and nosologic characteristics in the formed subgroups of patients there were calculated an integral risk of hospital-acquired infection development depending on terms of treatment in emergency room and index of severity of combined trauma by NISS. 50% risk of hospital-acquired infection development was determined to be on the 9th and 10th day of staying in emergency room with 4–5 strains of ESKAPE agents, firstly in the patients with craniltoracoabdonimoskeletal traumas that is 53.7 % from the study array.


Keywords


combined abdominal trauma; risk of hospital-acquired infection development; de-escalation antibiotic therapy

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DOI: https://doi.org/10.22141/1608-1706.4.16.2015.79946

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