Risk Factors of Osteoporosis in Primary Hypothyroidism

І.V. Pankiv


The objective of the study — to establish the incidence and risk factors of osteoporosis in women with primary hypothyroidism.
Material and methods. The study included 79 women with hypothyroidism. 37 women (46.8 %) had preserved menstrual cycle, 42 women (53.2 %) were in the postmenopausal period. Evaluation of bone mineral density was carried out by dual-energy X-ray absorptiometry.
Results. The incidence of osteoporosis in postmenopausal women was 38.1 % in the lumbar spine, 35.7 % — in the neck of the femur and 54.8 % — in the middle third of the forearm. In patients with preserved menstrual cycle, osteoporosis was diagnosed in the femoral neck (13.5 %), the middle third of the forearm (16.2 %) and in lumbar spine (8.1 %).
Conclusions. The development of osteoporosis in women with primary hypothyroidism is associated with factors related to both the disease (duration of hypothyroidism, levothyroxine daily dose) and traditional risk factor of osteoporosis — menopause.


primary hypothyroidism; osteoporosis; risk factors


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