State of Skeletal Muscle Tissue in Ukrainian Postmenopausal Women

V.V. Povoroznyuk, N.I. Dzerovych, A.S. Belinska, A.A. Palamarchuk


Today among geriatric syndromes, world scientists pay much attention to the study of sarcopenia. It was established that the evaluation of strength in skeletal muscles of the hand has a significant correlation with the risk of falling, disability, deterioration in the quality of life, duration of hospitalization. Further researches are needed to study the characteristics of the loss of weight, strength and function of skeletal muscles with age. The objective of this study was to explore the features of the loss of weight, strength and function of skeletal muscle tissue with age in postmenopausal women. The study involved 127 postmenopausal women, who, depending on age, were divided into groups: 50–59, 60–69, 70–79, 80–87 years. State of fat-free mass of the whole body, upper and lower extremities was evaluated using dual energy X-ray absorptiometry (Prodigy, GEHC Lunar, Madison, WI, USA). The strength of skeletal muscles was assessed using spring hand dynamometer. Functionality of skeletal muscles and the risk of falling was evaluated by tests: «two feet together», «semi-tandem», «tandem», «on one leg», «sit — stand», 8-step, 3-meter, 4-meter and 15-meter. The study found a probable decrease in fat-free mass with age at the level of lower extremities and appendiceal fat-free mass in women being examined. When assessing the strength of skeletal muscles using dynamometry, there was a tendency to decrease in its parameters in older age groups. When determining the functional capacity of skeletal muscles, there was found a significantly worse performance in people of older age groups during 15-meter test, a tendency to deterioration of «sit — stand», 3-meter, 4-meter and 8-step tests. When assessing static balance tests depending on age, there was revealed a tendency to decrease with age in the parameters of the following tests: «two feet together» «semi-tandem», «on one leg» and a probable decline in the performance of «tandem» test. Thus, in the older age groups, women have a significant decrease of appendiceal fat-free mass, the downward trend in skeletal muscle strength, significantly worse parameters of the functionality of skeletal muscles and the risk of falling.


weight; strength; functions; skeletal muscle tissue; women; postmenopause


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