Comparative Results of Comprehensive Treatment for Metastatic Bone Disease in Kidney Cancer Using Sorafenib

V.V. Protsenko, A.V. Ilnitskyi

Abstract


The article deals with the combined treatment of 56 patients with metastatic bone disease in renal cell carcinoma. The main group included 29 patients, in whom we have applied surgical treatment, radiation therapy, bisphosphonates (pamiredin, zoledronic acid) and targeted therapy (sorafenib) in the schemes of comprehensive treatment. As a result of the treatment, there has been achieved an improvement in the functional activity of the operated limb (excellent and good results — by 67.7 %), reduction of pain syndrome and survival rate of patients over 3 years (41.8 %) compared with 27 patients in the control group, who received radiotherapy, bisphosphonates, chemotherapy (5-fluorouracil), hormone therapy and immunotherapy.

Keywords


kidney cancer; bone metastases; complex treatment; surgical treatment; sorafenib

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DOI: https://doi.org/10.22141/1608-1706.2.16.2015.80263

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