Bone Mineral Density and Bone Health, Features of Constitution of Elderly Women with Osteoporotic Vertebral Deformities

Povorozniuk V.V. Povorozniuk V.V., Dzerovych N.I. Dzerovych N.I.

Abstract


For today, extraordinary attention of scientists is being paid to the study of associative changes in muscle and bone tissues with age. The reduction of muscle mass and its function is associated with reduced bone mineral density, increased risk of falls, decline in the quality of life, functionality and increased patients’ mortality. However, there was a small number of studies that have examined the relationship between sarcopenia and osteoporotic fractures. The objective of the study: to investigate particularities of body composition in women aged 65 years and more at the presence of vertebral deformities. We have examined 171 women aged 65–89 years. Depending on the presence of vertebral deformities, the patients were divided into two groups: A — 105 women without vertebral deformities, B — 66 women with vertebral deformities. Determination of fat, lean body mass, bone mineral density and bone health, roentgenomorphometry of vertebral bodies by means of LVA were carried out at dual-energy X-ray absorptiometer (Prodigy, GEHC Lunar, Madison, WI, USA). We determined that women with vertebral deformities compared with women without deformities have significantly lower indices of bone mineral density, trabecular bone score, fat and lean mass (p < 0.05). Incidence of presarcopenia (reduced lean mass) in women with vertebral deformities was 14.6 %, in women without deformities — 2.2 %.


Keywords


muscle tissue; lean mass; bone mineral density; osteoporosis; vertebral deformities; women

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DOI: https://doi.org/10.22141/1608-1706.6.15.2014.81794

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