Diagnosis of osteomalacia and osteoporosis in postmenopausal women


  • O.M. Ignatiev Odessa National Medical University, Odesa, Ukraine
  • M.I. Turchin Odessa National Medical University, Odesa, Ukraine
  • T.O. Ermolenko Odessa National Medical University, Odesa, Ukraine
  • O.D. Kichmarenko Odessa I.I. Mechnikov National University, Odesa, Ukraine




postmenopause, osteomalacia, osteoporosis, diagnosis


Despite a similar clinical outcome (fractures), morphostructural, etiological and pathogenetic characteristics, osteoporosis and osteomalacia differ qualitatively, and treatment regimens for these conditions will be different. To rule out a diagnostic error before prescribing treatment, the patient must undergo differential diagnostic measures to determine the cause of decreased bone mine-
ral density. We observed 65 postmenopausal women aged on ave-rage 62.30 ± 2.74 years, with reduced bone mineral density, who underwent morphological examination of bone tissue during hip arthroplasty for femoral neck fracture. X-ray densitometry was performed on Hologic Discovery bone densitometer (USA). Functional assessment of the musculoskeletal system was performed using the InsightTM device. The level of vitamin D (25(OH)D) in the blood serum was evaluated, as well as osteoprotegerin, C-terminal telopeptide of type 1 collagen, bone turnover marker. A mathematical model has been created that allows predicting the value of the morphological indicator “high functional activity of bone tissue cells” in osteomalacia and osteoporosis through other, the simplest and accessible laboratory parameters (25(OH)D, C-terminal telopeptide of type 1 collagen, osteoprotegerin), according to X-ray densitometry and examination on the InsightTM device (algometry and inclinometry).


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How to Cite

Ignatiev, O., Turchin, M., Ermolenko, T., & Kichmarenko, O. (2022). Diagnosis of osteomalacia and osteoporosis in postmenopausal women. TRAUMA, 23(1), 30–35. https://doi.org/10.22141/1608-1706.1.23.2022.879



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